Summary: Dosage math is simply managing the ratio of powder to water. Always convert your milligrams to micrograms (x1000) first to keep the units consistent. Stick to consistent "recipes" (like the 5mg + 2ml standard) so you become familiar with the numbers. And finally, always triple-check your calculation—or use a digital calculator—before drawing that first dose. In research, precision is safety.
“Peptide Math” is the single biggest barrier for new researchers. It feels complicated, but it follows a predictable, unbreakable logic. You are essentially diluting a solid mass into a liquid volume to create a specific concentration. This guide will walk you through the universal formula, provide standard “recipes,” and teach you how to use online tools so you never have to guess.
The Concepts: Mg vs. Mcg vs. Units vs. Ml
Before we do the math, we must define the language.
- Milligram (mg): The weight of the powder in the vial. This is the “Big Number” printed on the label.
- Microgram (mcg): The weight of the dose you want to take. This is the “Small Number.”
- The Golden Rule: 1 mg = 1,000 mcg. (Memorize this. 5mg = 5,000mcg).
- Milliliter (ml): The amount of water you add to the vial.
- Units: The tick marks on an insulin syringe.
- The Conversion: 1 ml = 100 Units (on a standard U-100 syringe).
The Universal Formula
To find out how many “Units” to pull on the syringe, follow this step-by-step logic.
Example Scenario:
- Vial: 5mg
- Water Added: 2ml (2 full syringes worth)
- Desired Dose: 250mcg
Step 1: Convert Vial Strength to Mcg
- 5mg x 1,000 = 5,000mcg total peptide in the vial.
Step 2: Find Concentration per Ml
- 5,000mcg / 2ml water = 2,500mcg in every 1ml of liquid.
Step 3: Find Concentration per Unit
- 2,500mcg / 100 Units = 25mcg per single Unit tick mark on the syringe.
Step 4: Calculate Your Draw
- Desired Dose (250mcg) / Concentration per Unit (25mcg) = 10 Units.
- Answer: You pull the syringe plunger to the “10” mark.
The “Cheat Sheet” Recipes
To avoid doing complex math every time, most researchers stick to a “Standard Mix” for common vial sizes. By always adding the same amount of water, the math stays the same.
Recipe A: The 5mg Standard (BPC-157, TB-500)
- Vial: 5mg
- Add: 2ml Water
- Result:
- 10 Units = 250mcg
- 20 Units = 500mcg
- 40 Units = 1000mcg (1mg)
Recipe B: The 2mg Mini (CJC-1295, Ipamorelin)
- Vial: 2mg (common for specialized peptides)
- Add: 1ml Water (Use less water for smaller vials)
- Result:
- 5 Units = 100mcg
- 10 Units = 200mcg
Recipe C: The 10mg Bulk (Tirzepatide, Semaglutide)
- Vial: 10mg
- Add: 2ml Water
- Result:
- 5 Units = 250mcg
- 10 Units = 500mcg
- 20 Units = 1000mcg (1mg)
Using a Peptide Calculator
In the modern age, you don’t need to do this in your head, especially if you are tired. Use a free online tool like the “PepCalc” app or “ PeptideCalc.com “.
1. Input 1: Vial Size (e.g., 5mg)
2. Input 2: Water Volume (e.g., 2ml)
3. Input 3: Desired Dose (e.g., 250mcg)
4. Output: The calculator will visually show you a picture of a syringe filled to the correct line (e.g., “10”).
- Tip: Always ensure the calculator is set to “U-100 Syringe” (the standard) to avoid errors.

