Peptide Directory
Category · 21 peptides
Cognitive & Nootropic
Peptides studied for focus, memory, mood, neuroprotection, and sleep.
9-Me-BCPreclinical
A synthetic β-carboline alkaloid studied preclinically for promoting dopaminergic neuron growth and boosting dopamine synthesis.- Enhanced dopamine levels
- Dopaminergic neurogenesis
- Neuroprotection
AdalankPreclinical
A vendor-formulated hybrid research peptide fusing Adamax-style cognitive enhancement with Selank-style anxiolysis in a single molecule.- Combined cognition and anxiolysis
- BDNF / TrkB upregulation
- GABAergic calm without sedation
AdamaxPreclinical
A designer Semax analog engineered for deeper brain penetration and a dramatically longer receptor-binding window than its parent nootropic.- BDNF and TrkB upregulation
- Dopaminergic D2 modulation
- Improved blood-brain-barrier penetration
BromantaneEmerging
A Russian adamantane-derived actoprotector that gently raises endogenous dopamine synthesis to deliver crash-free stimulation with an unusual anxiolytic, rather than anxiogenic, profile.- Motivation and drive
- Anxiety reduction
- Crash-free stimulation
CerebrolysinEmerging
A porcine brain-derived neuropeptide complex that mimics endogenous neurotrophic factors to support neuronal survival, plasticity, and recovery after brain injury.- Neuroprotection after acute injury
- Stroke and cognitive recovery
- Vascular dementia support
CerlutenEmerging
A Khavinson-class ultrashort peptide bioregulator proposed to protect neural tissue and support cognition through gene-expression regulation.- Neuroprotection
- Cognitive support
- Memory consolidation
CortexinEmerging
A porcine/bovine cortex-derived polypeptide bioregulator used clinically in Russia as a neuroprotective and nootropic agent.- Neuroprotection and neuronal survival
- Cognitive function improvement
- Antioxidant activity in CNS tissue
DavunetideEmerging
A synthetic ADNP-derived octapeptide investigated as a microtubule-stabilizing neuroprotectant for schizophrenia and tauopathies.- Microtubule stabilization
- Tau pathology protection
- Neuronal integrity biomarkers
DihexaPreclinical
A synthetic angiotensin IV-derived compound that potentiates HGF/c-Met signaling to drive synaptogenesis, with striking rodent potency but zero human trials.- Potent synaptogenesis
- Memory enhancement in animal models
- Hippocampal long-term potentiation (LTP)
DSIPPreclinical
A naturally occurring nine-amino-acid neuropeptide named for its association with delta-wave sleep, researched for decades for sleep architecture, stress modulation, and withdrawal support.- Sleep architecture support
- Stress and HPA-axis modulation
- Cortisol and ACTH regulation
FGLPreclinical
A synthetic 15-amino-acid NCAM-derived peptide that mimics neural cell adhesion molecule signaling to promote synaptic plasticity and neuroprotection in preclinical models.- Synaptic plasticity
- Memory enhancement
- Neuroprotection
HLDF-6Preclinical
A synthetic hexapeptide (TGENHR) derived from the HLDF protein, investigated preclinically for neuroprotection in Alzheimer's and Parkinson's models.- Neuroprotection
- Reduced amyloid-beta toxicity
- Memory enhancement
N-Acetyl SelankPreclinical
An acetylated derivative of the anxiolytic heptapeptide Selank, engineered for greater enzymatic stability and CNS bioavailability.- Anxiolytic effect
- Cognitive enhancement
- Memory support
N-Acetyl SemaxPreclinical
An acetylated (and often amidated) analog of the Russian nootropic Semax, engineered to resist enzymatic breakdown for longer-lasting cognitive and neuroprotective effects.- Cognitive enhancement
- BDNF and NGF upregulation
- Dopaminergic drive
NoopeptEmerging
A Russian-developed dipeptide nootropic roughly a thousand times more potent than piracetam, studied for memory, neuroprotection, and mild anxiolysis.- Memory consolidation
- BDNF and NGF upregulation
- Neuroprotection
P21Preclinical
A synthetic CNTF-derived neurotrophic peptide studied in rodents for driving hippocampal neurogenesis, BDNF expression, and memory while sparing the cachexia caused by full-length CNTF.- Hippocampal neurogenesis
- BDNF and neurotrophin upregulation
- Improved learning and memory
PE-22-28Preclinical
A synthetic humanin-derived peptide investigated in rodent models for antidepressant-like effects via glial glutamate transporter (GLT-1/EAAT2) upregulation.- Antidepressant-like activity (preclinical)
- Glutamate transporter (GLT-1/EAAT2) upregulation
- Neuroprotective / cytoprotective signaling
PinealonPreclinical
A Khavinson-class synthetic tripeptide (Glu-Asp-Arg) targeted at the pineal gland and brain, studied preclinically for neuroprotection, antioxidant defense, and circadian support.- Neuroprotection against oxidative stress
- Synapse and dendritic-spine preservation
- Epigenetic gene-expression modulation
SelankEmerging
A Russian-approved tuftsin-derived heptapeptide that delivers anxiolysis without the sedation, tolerance, or dependence of benzodiazepines.- Anxiolysis without sedation
- No tolerance, dependence, or withdrawal
- BDNF upregulation and cognitive support
SemaxEmerging
A Russian-developed ACTH(4-10) heptapeptide that rapidly upregulates BDNF for focus, neuroprotection, and stroke recovery without stimulating cortisol.- Rapid BDNF and NGF upregulation
- Neuroprotection and stroke recovery
- Cognitive performance and focus enhancement
VIPEmerging
A 28-amino-acid neuropeptide that binds VPAC1/VPAC2 receptors to drive potent anti-inflammatory, vasodilatory, and circadian-regulating effects across the nervous, immune, and vascular systems.- Potent anti-inflammatory signaling
- Neuroprotection
- Circadian rhythm regulation
